TOPICAL ANESTHETICS:
The below mentioned
article describes the use of
LAT Gel (Lidocaine,
adrenaline, and tetracaine)
for use on facial and scalp
lacerations.
"LAT gel (4% lidocaine,
1:2000 adrenaline, 0.5%
tetracaine) worked as well
as TAC gel (0.5% tetracaine,
1:2000 adrenaline, 11.8%
cocaine) for topical
anesthesia in facial and
scalp lacerations.
Considering the advantages
of a noncontrolled substance
and less expense, LAT gel
appears to be better suited
than TAC gel for topical
anesthesia in laceration
repair in children."
Pediatrics
1995 Feb;95(2):255-8
Lidocaine adrenaline
tetracaine gel versus
tetracaine adrenaline
cocaine gel for topical
anesthesia in linear scalp
and facial lacerations in
children aged 5 to 17 years.
Ernst AA, Marvez E,
Nick TG, Chin E, Wood E,
Gonzaba WT
Department of Medicine,
Louisiana State University,
New Orleans.
In order to access the
PubMed abstract of this
article, visit this
website link.
The following article
reported that a
triple-anesthetic gel
containing benzocaine,
lidocaine, and tetracaine
("BLT") applied prior to
treatment with a 532-nm KTP
laser resulted in
significantly lower pain
scores than with 3 other
topical anesthetics at 15,
30, 45, and 60 minutes after
application.
Cosmetic Dermatology
2003 Apr;16(4):35-7
Topical
Triple-Anesthetic Gel
Compared With 3 Topical
Anesthetics
Lee MWC
Department of Dermatologic
Surgery, University of
California, San Francisco
TOPICAL
OPIOIDS:
The below mentioned article
describes how topical
morphine gel has proved a
rapid reduction in pain when
acute inflammatory pain was
present.
"The use of topical morphine
gel is reported in two
children with epidermolysis
bullosa, where acute
inflammatory pain is a major
symptom and where effective
analgesia is a major
clinical problem. The gel
provided rapid reduction in
pain scores in the patients
and without any reported
adverse effects or
tolerance. A topical route
of analgesia might be
extremely beneficial for
children with other painful
skin lesions, including
burns or post-surgical
wounds, and further studies
are now required."
Arch Dis Child. 2004 Jul;89(7):679-81
Peripheral opioids in
inflammatory pain.
In order to access the
PubMed abstract of this
article, visit this
website link.
Morphine sulfate 10 mg in Intrasite gel was
applied topically to skin
ulcers of hospice
inpatients. The topical
morphine was not absorbed in
the majority of patients,
suggesting any analgesic
effect was mediated locally
rather than systemically.
J Pain Symptom Manage. 2004 May;27(5):434-9
The bioavailability of
morphine applied topically
to cutaneous ulcers.
In order to access the
PubMed abstract of this
article, visit this
website link.
